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Showing 10 results for Roudsari

Sedigheh Ayaty, Fatemeh Vahid Roudsari, Fatemeh Tavassoly,
Volume 5, Issue 3 (7-2007)

Background: CA-125 is a glycoprotein and its origin is uncertain during pregnancy. It arises during the first trimester and return to a non-pregnancy range in late pregnancy.
Objective: The aim of this study was to compare CA-125 level in threatened abortion and normal pregnancy less than 20 weeks of pregnancy.
Materials and Methods: This was a prospective case study carried out on 50 healthy pregnant (group 1) and 50 threatened abortion women (group 2). We compared the levels of CA-125 in these groups and followed them to be informed of the outcome of pregnancy.
Results: Fifty percent of women were in 20-24 years old group, primigravida and in the first trimester of pregnancy. The mean level of CA-125 in group 1 was 26.2 ± 3.25 IU/ml and in group 2 was 37.44 ± 2.72 IU/ml. The mean level of CA-125 in finally aborted patients was 58.17±7.25 IU/ml and in normal pregnant women, who continue to term, was 26.61±1.76 IU/ml. The CA-125 level in threatened women,whose pregnancy continued and did not abort, was 30.89 IU/ml. There was statistically significant difference between mean serum CA-125 levels of two groups (p < 0.05), while there was no statistically significant difference between these levels in the patients of both groups who continued pregnancies (p > 0.1). In group 2, there was a statistically significant difference in the level of CA-125 between those who developed abortion and those whose pregnancy continued but not aborted (p < 0.05).
Conclusion: Measurement of serum CA-125 may be an inexpensive, easily available, sensitive and specific predictor of outcome in threatened abortion, which results the loss of pregnancy.
Fatemeh Vahid Roudsari, Sedigheh Ayati, Hossein Ayatollahi, Habibollah Esmaeily, Maliheh Hasanzadeh, Masoud Shahabian, Leila Pour Ali,
Volume 7, Issue 4 (7-2009)

Background: Preeclampsia is a disorder unique to pregnancy and has long been recognized as an important contributor of maternal and fetal morbidity and mortality. It is suggested that cytokines such as Tumor Necrosis Factor-alpha (TNF-α) have an important role in the pathogenesis of preeclampsia and may cause generalized endothelial dysfunction.
Objective: The aim of this study was comparison of maternal serum TNF-α in severe and mild preeclampsia versus normal pregnancy.
Materials and Methods: This study was performed on 37 women with preeclampsia (17 mild and 20 severe preeclampsia) and 41 normotensive pregnant women with similar gestational age at third trimester of pregnancy. All the preeclamptic cases had blood pressure ≥ 140/90 mmHg and proteinuria ≥ 300 mg in a 24-h urine sample. Maternal serum TNF-α concentration was compared in all of them.
Results: The level of TNF-α concentration was not statistically different between the studied groups. No significant correlation was found between preeclampsia and control group as they were compared in the view of maternal serum TNF-α concentration.
Conclusion: These findings suggest that serum TNF-α is not significantly associated with preeclampsia.
Tahmineh Farajkhoda, Robab Latifnejad Roudsari, Mahmoud Abbasi,
Volume 11, Issue 1 (4-2013)

Background: Research in reproductive health (RH) has been located in the core of women’s health research. Providing accurate information through conducting scientific and controlled research is essential, but increased number of research in the world especially in developing countries in RH area in order to introduce advanced technologies has been resulted in much unethical, illegal and abusive research on women, which needs particular attention to ethical issues by the practitioners who are involved in RH research.
Objective: This study was conducted to develop a practical ethical framework for RH research.
Materials and Methods: 45 expert academics and clinicians in various disciplines included in a three rounds Delphi study through purposeful sampling method. In round 1 Delphi data were gathered using open-ended questions by e-mail and answers were analyzed by conventional content analysis and the findings merged and validated with the results of a thorough literature review. Face and content validity index were determined in round 2 Delphi and consensuses were attained in round 3.
Results: Emerged categories were 1) management of the research process 2) protection of participants’ rights 3) third party consent 4) gender sensitive research and 5) conflict of interest.
Conclusion: This study has provided a practical ethical framework according to the socio-cultural context of Iran for all practitioners who are involved in research on women. Adherence to this framework may protect practitioners against unethical and illegal lawsuits and help them to respect their clients’ reproductive rights.
Robab Latifnejad Roudsari, Mojgan Javadnoori, Marzieh Hasanpour, Seyyed Mohammad Mehdi Hazavehei, Ali Taghipour,
Volume 11, Issue 2 (4-2013)

Background: Despite clear reasons for necessity of sexual health education for adolescents, it is a contested issue and has faced challenges in most cultures. Providing sexual education for non-married adolescents is culturally unacceptable in most Muslim societies.
Objective: This qualitative study addressed socio-cultural challenges to sexual health education for female adolescents in Iran.
Materials and Methods: Qualitative data from female adolescents (14-18 yr), mothers, teachers, authorities in health and education organizations, health care providers and clergies were collected in two large cities of Iran including Mashhad and Ahvaz through focus group discussions and individual in-depth interviews. Data were analyzed using conventional qualitative content analysis with MAXqda software.
Results: Our results revealed that the main socio-cultural challenges to sexual health education for adolescents in Iran are affected by taboos surrounding sexuality. The emergent categories were: denial of premarital sex, social concern about negative impacts of sexual education, perceived stigma and embarrassment, reluctance to discuss sexual issues in public, sexual discussion as a socio-cultural taboo, lack of advocacy and legal support, intergenerational gap, religious uncertainties, and imitating non-Islamic patterns of education.
Conclusion: It seems that cultural resistances are more important than religious prohibitions, and affect more the nature and content of sexual health education. However, despite existence of salient socio-cultural doubtful issues about sexual health education for adolescents, the emerging challenges are manageable to some extent. It is hoped that the acceptability of sexual health education for adolescents could be promoted through overcoming the cultural taboos and barriers as major obstacles.
Talat Khadivzadeh, Robab Latifnejad Roudsari, Masoud Bahrami, Ali Taghipour, Jalal Abbasi Shavazi,
Volume 11, Issue 3 (5-2013)

Background: Recently, the relevance of social interactions as determinants of behavioral intentions has been increasingly perceived, but there is a lack of knowledge on how and why it interacts with couples’ fertility intentions.
Objective: This qualitative study was conducted to explore the influence of social network on couples’ intention to have their first child in urban society of Mashhad, Iran in 2011.
Materials and Methods: In this exploratory qualitative study in-depth interviews were conducted with 24 participants including 14 fertile women, two parents, three husbands and five midwives and health care providers. The sample was selected purposively in urban health centers, homes and workplaces until data saturation was achieved. Data analysis was carried out adopting conventional content analysis approach through giving analytical codes and identification of categories using MAXqda software. Study rigor verified via prolonged engagement, validation of codes through member check and peer debriefing.
Results: Findings from data analysis demonstrated four major categories about social network’s influence on couples’ intention to have their first child including 1) perception of fertility relevant social network, 2) occurrence of various types of social influence 3) subjective judgment to the benefits of social network and its fitness to personal life, and 4) couples’ interaction with social network.
Conclusion: Managing the fertility behaviors need to include the consideration of personal social networks surrounding the couples. It is important to apply the study findings in providing family planning services and dissemination of appropriate fertility behaviors through community-based reproductive health care delivery system.
Masumeh Ghazanfarpour, Ramin Sadeghi, Somayeh Abdolahian, Robab Latifnejad Roudsari,
Volume 14, Issue 3 (3-2016)

Background: Hot flashes are the most common symptoms experienced by women around the time of menopause. Many women are interested in herbal medicines because of fear of side effects of hormone therapy.
Objective: The aim of this systematic review was to assess the effectiveness of Iranian herbal medicines in alleviating hot flashes.
Materials and Methods: MEDLINE (1966 to January 2015), Scopus (1996 to January 2015), and Cochrane Central Register of Controlled Trials (The Cochrane Library, issue 1, 2015) were searched along with, SID, Iran Medex, Magiran, Medlib and Irandoc. Nineteen randomized controlled trials met the inclusion criteria.
Results: Overall, studies showed that Anise (Pimpinella anisum), licorice (Glycyrrhizaglabra), Soy, Black cohosh, Red clover, Evening primrose, Flaxseed, Salvia officinalis, Passiflora، itex Agnus Castus, Piascledine (Avacado plus soybean oil), St. John's wort (Hypericum perforatum), and valerian can alleviate the side effects of hot flashes.
Conclusion: This research demonstrated the efficacy of herbal medicines in alleviating hot flashes, which are embraced both with people and health providers of Iran Therefore, herbal medicine can be seen as an alternative treatment for women experiencing hot flashes.
Nahid Maleki-Saghooni, Malihe Amirian, Ramin Sadeghi, Robab Latifnejad Roudsari,
Volume 15, Issue 7 (8-2017)

Background: Psychological interventions such as counseling for infertile patients seem to increase pregnancy rate.
Objective: The aim of this systematic review and meta-analysis was to examine if counseling improves pregnancy rate among infertile patients. Thus, randomized controlled trials investigating the effect of counseling on pregnancy rate in infertile patients undergoing ART were pooled in a meta-analysis.
Materials and Methods: The databases of PubMed, Scopus, Cochrane, Google Scholar, and Persian databases including SID, Iran Medex, and Magiran were searched from 1997 to July 2016 to identify relevant articles. Included studies were trials on infertile patients (women or couples) receiving counseling independent of actual medical treatment. The outcome measure was pregnancy rate. Out of 620 relevant published trials, a total of nine RCTs were ultimately reviewed systematically and included in a meta-analysis to measure the efficacy of counseling on pregnancy rate. Odds ratio and Risk difference were calculated for pregnancy rate. All statistical analyses were done by Comprehensive Meta-analysis Version 2.
Results: Nine RCTs involving 1079 infertile women/couples were included in the study. The findings from RCTs indicated significant effect of counseling on pregnancy rate so that there was a positive impact of counseling on pregnancy rate (OR= 3.852; 95% CI: 2.492-5.956; p=0.00) and (RD= 0.282; 95%; CI: 0.208-0.355; p=0.00).
Conclusion: Counseling was found to improve patients’ chances of becoming pregnant. So counseling represents an attractive treatment option, in particular, for infertile patients who are not receiving medical treatments.
Maryam Zamani, Robab Latifnejad Roudsari, Maryam Moradi, Habibollah Esmaily,
Volume 17, Issue 1 (January 2019 2019)

Background: Many couples experience decreasing sexual satisfaction in postpartum period. Various sexual health counseling approaches have been designed for postpartum women to address their common sexual concerns and problems.
Objective: This study aimed to investigate the effectiveness of Women’s Postpartum Sexual Health Program (WPSHP) on women’s sexual satisfaction in postpartum period.
Materials and Methods: The study was a single blind randomized clinical trial on 75 postpartum women aged 18–35 yr with low sexual satisfaction who attended urban health-care centres in Mashhad, Iran in 2016. Data were collected using a demographic questionnaire, the Depression Anxiety Stress Scales-21, and the Larson Sexual Satisfaction Questionnaire. The intervention group received counselling based on the WPSHP, a four-session, group- and couples-based program. The control group  just received postpartum routine care.
Results: Both the intervention and control groups were homogeneous for demographic variables. According to the Mann-Whitney test, sexual satisfaction score in the  intervention group was significantly higher than the control group 8 weeks after the intervention (p < 0.001). According to the Wilcoxon test, there was a significant difference in the mean score of sexual satisfaction before and after intervention in the intervention group (p < 0.001).
Conclusion: WPSHP caused higher levels of sexual satisfaction. It is therefore recommended to use this program in women during the postpartum period to promote their sexual satisfaction.
Robab Latifnejad Roudsari, Hamideh Jafari, Ali Taghipour,
Volume 17, Issue 5 (May 2019 2019)

Background: There are controversial views on accepting a reproductive donation inthe world.
Objective: This study aimed to determine the relationship between the socioculturalbeliefs and infertile couples’ attitude toward reproductive donation in Mashhad, Iran.

Materials and Methods: This descriptive correlational study was conducted out on 115infertile couples visiting Milad Infertility Center in Mashhad, Iran with using conveniencesampling. The research instruments were valid and reliable sociocultural beliefs andattitude questionnaires, which were completed by the respondents on a self-reportbasis.Results:The mean score of attitude toward reproductive donation in infertile womenand men was 58.3±12.6 and 57.8±12.0, and the mean score of sociocultural beliefs ininfertile women and men was 67.7±11.5 and 67.6±12.4, respectively. There was a directcorrelation between sociocultural beliefs and attitude toward reproductive donationin infertile women (p<0.001) and men (p<0.001), that is, women and men with ahigher score of sociocultural beliefs had a higher score of attitude as well. A directcorrelation was also seen between sociocultural beliefs and infertile women and men’spublic attitude, their attitude towards genetic bound between parents and children,their attitude regarding the issue of confidentiality of the donation process, as well asattitude in relation to oocyte donation, embryo donation, and surrogacy (p<0.001).
Conclusion: The findings suggest that sociocultural beliefs that surround reproductivedonation could influence infertile couple’s attitude toward accepting these therapeuticalternatives in infertile couples. It is therefore recommended to take steps toincorporate sociocultural beliefs into the routine care of infertile couples with the helpof social media to give them ability for making more pragmatic decision in relation totheir chosen options

Samira Ebrahimzadeh Zagami, Roksana Janghorban, Robab Latifnejad Roudsari,
Volume 18, Issue 1 (January 2020)

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