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Showing 5 results for Jamil

Aisha Javed, Saeed Rezaei-Zarchi, Morteza Anvari, Madiha Javeed Ghani, Fatemeh Barzegari Firouzabadi, Amer Jamil, Seyed Mehdi Kalantar, Habibollah Nazem,
Volume 6, Issue 5 (7-2008)

Background: In vitro maturation (IVM) of oocytes reduces the costs and averts the side-effects of gonadotropin stimulation for in vitro fertilization (IVF). Reliable IVM is an intellectual, scientific and clinical challenge with a number of potential applications.
Objective: The effect of hCG was evaluated on the timing and regulation of in vitro ovulation for the Syrian mice oocytes in the presence and absence of FSH. 
Materials and Methods: Preantral follicles, isolated from the ovaries of 6 weeks-old mice, were cultured in TCM-199 medium. The effect of 10-200 mIU/ml FSH and 1.5 IU/ml hCG was seen on the follicle maturation, as well as the changes in ovulation capacity of enclosed oocytes, after the incubation period of 6 days at 37 °C, 92% humidity and 5% CO2 in air.
Results: 100 mIU/ml FSH showed increased follicle diameter, survival, germinal vesicle breakdown (GVBD) and oocyte maturation rates (p<0.0001). Significantly higher number of follicles showed cumulus attachment when ovulation started within 16-24 hours post hCG (97% and 80% respectively; p<0.0001) as compared to the cultures without hCG or when the ovulation time increased from 24 hours post hCG. Combination of FSH and hCG showed 97% (p<0.0001) ovulation as compared to that seen for FSH-containing medium only (81%) or control (10%).
Conclusion: The combined administration of 1.5 IU/ml hCG and 100 mIU/ml FSH induces the in vitro follicle maturation, ovulation capacity and proper timing of mice oocytes. 
Fatemeh Mirzaie, Nahid Eftekhari, Sedigheh Goldozeian, Jamileh Mahdavinia,
Volume 8, Issue 2 (7-2010)

Background: Anemia in pregnancy is associated with increased rates of maternal and perinatal mortality.
Objective: To study the prevalence and risk factors of women with anemia during pregnancy in Kerman, Iran.
Materials and Methods: A retrospective cross-sectional study was performed based on 2213 pregnancies delivered during the years 2005-2007 in Kerman, Iran. Women with hemoglobinopathies such as thalassemia were excluded from analysis. Anemia was defined as hemoglobin (Hg) lower than 11 g/dl during pregnancy. Categorical variables were compared using the chi-square or Fisher’s exact test.
Results: Overall, 104 (4.7%) women were anemic (Hg<11g/dl), out of which 4.8% had severe anemia (Hg<7g/dl), 15.4 % had moderate anemia (Hg=7-8.9 g/dl) and 79.8% had mild anemia (Hg=9-10.9 g/dl). The frequency of anemia were 5%, 3.4% and 5.7% in the first, second and third trimester, respectively. Multiparity was associated with lower hemoglobin concentration during the second/third trimester of pregnancy (p=0.03 and p<0.001, respectively). Prevalence of anemia was significantly higher in smokers and opium users (p=0.01 and p=0.003, respectively).
Conclusion: Our study showed that prevalence of anemia was not high in this study. Factors associated with anemia during pregnancy were parity, smoking, opium use and not using Iron supplement.
Sedigheh Amooee, Alamtaj Samsami, Jamileh Jahanbakhsh, Mehran Karimi,
Volume 9, Issue 1 (7-2011)

Background: β-thalassemia is the most common hereditary disease in Iran and more than 2 million carriers of the β-thalassemia mutant gene are living in this country.
Objective: To determine pregnancy outcome of women with β-thalassemia minor.
Materials and Methods: In this retrospective, case-control study in two universities affiliated hospitals in Shiraz, all pregnancies occurred between 2006 and 2008 were included. Patients were divided in two groups regarding the presence of β-thalassemia minor. Patients in case and control groups were matched according to maternal age, gestational age and number of previous pregnancies. Cesarean delivery, hypertensive disorders, gestational diabetes mellitus, premature rupture of membranes and preterm labor were recorded in each group and were compared using the χ2 or Fisher exact tests. 
Results: Overall 510 β-thalassemia minor subjects and 512 healthy controls were studied. Cases with β-thalassemia minor had significantly higher prevalence of oligohydramnios (p<0.001) and cesarean section delivery (p=0.001). There was no significant difference regarding Apgar score in 1st (p=0.65) and 5th minute (p=0.25), IUGR (p=0.073), gestational diabetes mellitus (DM) (p=0.443) and preeclampsia (p=0.116) between two study groups.    
Conclusion: β-thalassemia minor does not significantly influence the pregnancy outcome in the negative way.
Mehri Jamilian,
Volume 12, Issue 2 (2-2014)

Background: The incidence of ectopic pregnancy varies between 1.5-2% of all pregnancies. Bilateral tubal ectopic pregnancy is rare. It may occur in 1 per 200 000 pregnancies.
Case: This is a case report of 25 year-old woman who underwent intra uterine insemination (IUI), because of tubal factor infertility (unilateral). On the 30th day after the IUI she complained from pelvic pain and vaginal bleeding. Pelvic ultrasound showed bilateral tubal ectopic pregnancy with fluid in Douglas Pouch and empty uterine cavity. Exploratory laparotomy, left salpingectomy, and right salpingostomy were performed on the same day of admission.
Conclusion: The above case suggests that cases presenting with infertility and ectopic pregnancy should be followed very closely with β-hCG and or Trans Vaginal Sonography (TVS) to exclude double ectopic. So, as in this case, early diagnosis is essential for prevention of maternal morbidity and mortality.

Hadise Aslfalah, Mehri Jamilian, Hadi Ansarihadipour, Mahdi Abdollahi, Ali Khosrowbeygi,
Volume 18, Issue 12 (December 2020)

Background: Evidence suggests that Oxidative stress has been shown to plays an important role in gestational diabetes mellitus (GDM) etiology. On the other hand, women with GDM are at an increased risk for complications such as endothelial dysfunction and cardiovascular diseases.
Objective: To investigate the effects of alpha-lipoic acid (ALA) on the maternal circulating values of lipid profile and lipid ratios in women with GDM.
Materials and Methods: Sixty women with GDM were participated in the present study. The ALA group (n = 30) received ALA (100 mg/day) and the placebo group (n = 30) received cellulose acetate (100 mg/day) for eight wk. The maternal circulating values of hemoglobin A1C, triglyceride (TG), total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, triglyceride-glucose (TyG) index, atherogenic index of plasma (AIP), non-HDL-C, and lipid ratios were assessed before and after the intervention. P-value < 0.05 was considered as statistically significant.
Results: The values of TyG index (p < 0.001), TG (p = 0.006), TG/HDL-C (p = 0.003), and AIP (p = 0.005) decreased significantly in the ALA group after the intervention.
Conclusion: Maternal circulating values of TyG index, TG, TG/HDL, AIP decreased after eight wk of ALA supplementation in women with GDM.

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