Volume 15, Issue 10 (12-2017)                   IJRM 2017, 15(10): 601-612 | Back to browse issues page

DOI: 10.29252/ijrm.15.10.2

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1- Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran
2- Genetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
3- Center for Reproductive Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
4- Reproductive Medicine Unit, University of Schleswig-Holstein, Luebeck, Germany
5- Yildiz Technical University, Istanbul, Turkey
6- Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran , Akhondi@Avicenna.ac.ir
Abstract:   (985 Views)
Nuclear transfer procedures have been recently applied for clinical and research targets as a novel assisted reproductive technique and were used for increasing the oocyte activity during its growth and maturation. In this review, we summarized the nuclear transfer technique for germinal vesicle stage oocytes to reconstruct the maturation of them. Our study covered publications between 1966 and August 2017. In result utilized germinal vesicle transfer techniques, fusion, and fertilization survival rate on five different mammalian species are discussed, regarding their potential clinical application. It seems that with a study on this method, there is real hope for effective treatments of old oocytes or oocytes containing mitochondrial problems in the near future.
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Type of Study: Original Article |

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