Volume 11, Issue 5 (7-2013)                   IJRM 2013, 11(5): 371-0 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Bazarganipour F, Ziaei S, Montazeri A, Foroozanfard F, Faghihzadeh S. Health-related quality of life and its relationship with clinical symptoms among Iranian patients with polycystic ovarian syndrome. IJRM. 2013; 11 (5) :371-0
URL: http://journals.ssu.ac.ir/ijrmnew/article-1-426-en.html
1- Department of Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2- Department of Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran , ziaei_sa@modares.ac.ir
3- Mental Health Research Group, Health Metrics Research Center, Iranian Institute for Health Sciences Research, ACECR, Tehran, Iran
4- Department of Obstetrics and Gynecology, Kashan University of Medical Sciences, Kashan, Iran
5- Faculty of Medical Sciences, Zanjan University of Medical Sciences, Zanjan, Iran
Abstract:   (545 Views)
Background: Polycystic ovarian syndrome (PCOS) has been shown to cause a reduction in Health-related quality of life (HRQOL).
Objective:  This study examines the extent of different clinical symptoms in PCOS patients on HRQOL.
Materials and Methods:  A cross-sectional study was undertaken to ascertain the factors related to HRQOL in 200 PCOS patients in Kashan, Iran. Main outcome measures were modified polycystic ovarian syndrome questionnaire (MPCOSQ) and clinical information of PCOS. Major clinical PCOS features including obesity (BMI), excessive body hair (hirsutism score), acne, menstrual cycle disturbances and infertility.
Results:  Findings showed that the most common HRQOL concern was menstrual irregularities and infertility, followed in descending order by hirsutism, weight, emotion, and acne. Multivariate analysis revealed the menstrual irregularities as a significant predictor of menstruation (p=0.005), emotion (p=0.02) and infertility (p=0.02) subscales of the MPCOSQ. Having of infertility, predicted scores on the infertility subscale (p<0.0001). Hirsutism score was a significant predictor of hirsutism (p<0.0001) and emotion (p<0.0001) subscales. Weight subscale concerns was predicted by BMI (p<0.0001), also, acne was found to be predicted score of acne subscale (p<0.0001).
Conclusion:  Worsened HRQOL in women with PCOS was related to more menstrual irregularities and infertility than to obesity. The finding suggests a potential for poorer compliance with weight management protocols among affected PCOS patients.
Full-Text [PDF 651 kb]   (92 Downloads) |   |   Full-Text (HTML)  (56 Views)  
Type of Study: Original Article |

References
1. Ehrmann DA. Polycystic ovary syndrome. N Engl J Med 2005; 352: 1223-1236. [DOI:10.1056/NEJMra041536]
2. Hahn S, Janssen OE, Tan S, Pleger K, Mann K, chedlowski M, et al. Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. Euro J Endocrinol 2005; 153: 853-860. [DOI:10.1530/eje.1.02024]
3. Elsenbruch S, Hahn S, Kowalsky D, Offner AH, Schedlowski M, Mann K, et al. Quality of life, psychosocial well-being and sexual satisfaction in women with polycystic ovary syndrome. J Clin Endocr Metab 2003; 88: 5801-5807. [DOI:10.1210/jc.2003-030562]
4. Coffey S, Bano G, Mason H. Health-related quality of life in women with polycystic ovary syndrome: a comparison with the general population using the polycystic ovary syndrome questionnaire (PCOSQ) and the Short Form-36 (SF-36). Gynecol Endocrinol 2006; 22: 80-86. [DOI:10.1080/09513590600604541]
5. Ching HL, Burke V, Stuckey BG. Quality of life and psychological morbidity in women with polycystic ovary syndrome: body mass index, age and the provision of patient information are significant modifiers. Clin Endocrinol (Oxf) 2007; 66: 373-379. [DOI:10.1111/j.1365-2265.2007.02742.x]
6. Wright J, Duchesne C, Saboutin S, Bissonnette F, Benoit J, Girad Y. Psychosocial distress and infertility, men and women respond differently. Fertil Steril 1991; 55: 100-108. [DOI:10.1016/S0015-0282(16)54067-9]
7. Sarlio-Lahteenkorva S, Stunkard A, Rissanen A. Psychosocial factorsand quality of life in obesity. Int J Obes Relat Metab Disord 1993; 19 (Suppl.): 1-25.
8. Kitzinger C, Willmott J. The thief of womanhood': women's experience of polycystic ovarian syndrome. Soc Sci Med 2002; 54: 349-361. [DOI:10.1016/S0277-9536(01)00034-X]
9. Colwell H, Mathias S, Pasta D, Henning J, Steege J. A health-related quality of life instrument for symptomatic patients with endometriosis: A validation study. Am J Obstet Gynecol 1998; 179: 47-55. [DOI:10.1016/S0002-9378(98)70250-9]
10. Mant D, Fowler G. Mass screening: Theory and ethics. BMJ 1990; 300: 916-918. [DOI:10.1136/bmj.300.6729.916]
11. Streiner D. Health measurement scales: A practical guide to their development and use. Oxford, UK: Oxford University Press; 1995.
12. Jones GL, Hall JM, Balen AH, Ledger WL. Health-related quality of life measurement in women with polycystic ovary syndrome: a systematic review. Hum Reprod Update 2008; 14: 15-25. [DOI:10.1093/humupd/dmm030]
13. Hashimoto DM, Schmid J, Martins FM, Fonseca AM, Andrade LH, Kirchengast S, et al. The impact of the weight status on subjective symptomatology of the polycystic ovary syndrome: a cross-cultural comparison between Brazilian and Austrian women. Anthropol Anz 2003; 61: 297-310.
14. Ramezani Tehrani F, Simbar M, Tohidi M, Hosseinpanah F, Azizim F. The prevalence of polycystic ovary syndrome in a community sample of Iranian population: Iranian PCOS prevalence study. Reprod Biol Endocrinol 2011; 9: 39. [DOI:10.1186/1477-7827-9-39]
15. Cronin L, Guyatt G, Griffith L, Wong E, Azziz R, Futterweit W, et al. Development of a health-related quality-of-life questionnaire (PCOSQ) for women with polycystic ovary syndrome (PCOS). J Clin Endocrinol Metab 1998; 83: 1976-1987.
16. Barnard L, Ferriday D, Guenther N, Strauss B, Balen AH, Dye L. Quality of life and psychological well being in polycystic ovary syndrome. Hum Reprod 2007; 22: 2279-2286. [DOI:10.1093/humrep/dem108]
17. Bazarganipour F, Ziaei S, Montazeri A, Faghihzadeh S, Frozanfard F. Psychometric properties of the Iranian version of modified Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire. Hum Reprod 2012; 27: 2729-2736. [DOI:10.1093/humrep/des199]
18. Ferriman D, Gallwey JD. Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 1961; 21: 1440-1447. [DOI:10.1210/jcem-21-11-1440]
19. Winkvist A, Akhtar HZ. God should give daughters to rich families only: attitudes toward childbearing among low-income women in Punjab, Pakistan. Soc Sci Med 2000; 51: 73-78. [DOI:10.1016/S0277-9536(99)00440-2]
20. Penn R, Lambert P. Attitudes toward ideal family size of different ethnic/nationality groups in Great Britain, France and Germany. Popular Trends 2002; 108: 49-58.
21. Guz H, Ozkan A, Sarisoy G, Yanik F, Yanik A. Psychiatric symptoms in Turkish infertile women. J Psychosomat Obset Gynecol 2003; 24: 267-271. [DOI:10.3109/01674820309074691]
22. McCook J, Reame N, Thatcher S. Health-related quality of life issues in women with polycystic ovary syndrome. J Obstet Gynecol Neonatal Nurs 2005; 34: 12-20. [DOI:10.1177/0884217504272945]
23. Shulman LH, DeRogatis L, Spielvogel R, Miller JL, Rose LI. Serum androgens and depression in women with facial hirsutism. J Am Acad Dermatol 1992; 27: 178-181. [DOI:10.1016/0190-9622(92)70166-D]
24. Weber B, Lewicka S, Deuschle M, Colla M, Heuser I. Testosterone, androstenedione and dihydrotestosterone concentrations are elevated in female patients with major depression. Psychoneuroendocrinology 2000; 25: 765-771. [DOI:10.1016/S0306-4530(00)00023-8]
25. Weiner CL, Primeau M, Ehrmann DA. Androgens and mood dysfunction in women: comparison of women with polycystic ovarian syndrome to healthy controls. Psychosom Med 2004; 66: 356-362.
26. Schmid J, Kirchengast S, Vytiska-Binstorfer E, Huber J. Infertility caused by PCOS--health-related quality of life among Austrian and Moslem immigrant women in Austria. Hum Reprod 2004; 19: 2251-2257. [DOI:10.1093/humrep/deh432]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2020 All Rights Reserved | International Journal of Reproductive BioMedicine

Designed & Developed by : Yektaweb