Volume 16, Issue 3 (March 2018)                   IJRM 2018, 16(3): 209-212 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mirzaei A, Piri S, Gharanizadeh K, Zabihiyeganeh M. Undesired effect of excessive betamethasone administration during pregnancy: A rare case . IJRM. 2018; 16 (3) :209-212
URL: http://journals.ssu.ac.ir/ijrmnew/article-1-1024-en.html
1- Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran
2- National Association of Iranian Gynecologists and Obstetrician, Tehran, Iran
3- Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran , mozhdehzabihi@gmail.com
Abstract:   (696 Views)
Background: Postpartum bilateral femoral neck fracture (BFNF) is a rare condition. We here report a case of BFNF due to excessive corticosteroid consumption, twin pregnancy, immobility, and vitamin D deficiency.
Case: This is a report of a 32-yr-old woman with bilateral femoral insufficiency fracture five days after emergency cesarean section due to preterm labor, twin pregnancy, and the history of a previous cesarean section at 33 wk. Antenatal repeated courses of betamethasone injections for fetal lung maturity, daily oral use of prednisolone for the history of miscarriage, immobilization, and vitamin D deficiency were the important contributing factors in her past medical history and lab investigations. The bone mineral density examination showed low bone density for the expected age.
Conclusion: Clinicians, who deal with pregnant women, should consider the diagnosis of bilateral femoral insufficiency fracture in any pregnant women with pelvic pain. Awareness of risk factors of BFNF might help to reduce the rate of this complication.
Full-Text [PDF 488 kb]   (196 Downloads) |   |   Full-Text (HTML)  (121 Views)  
Type of Study: Case Report |

References
1. Uzun E, Günay AE, Kızkapan TB, Mutlu M. Atraumatic diplaced bilateral femoral neck fracture in a patient with hypophosphatemic rickets in postpartum period: A missed diagnosis. Int J Surg Case Rep 2016; 28: 321-324. [DOI:10.1016/j.ijscr.2016.10.028]
2. Hadji P, Boekhoff J, Hahn M, Hellmeyer L, Hars O, Kyvernitakis I. Pregnancy-associated transient osteoporosis of the hip: results of a case-control study. Arch Osteoporos 2017; 12: 11. [DOI:10.1007/s11657-017-0310-y]
3. Kovacs CS. Calcium and bone metabolism disorders during pregnancy and lactation. Endocrinol Metab Clin North Am 2011; 40: 795-826. [DOI:10.1016/j.ecl.2011.08.002]
4. Yassin A, Jawad I, Coomber R, Gonzalez-Castro A. Non-traumatic, bilateral subcapital femoral fractures postpartum. BMJ Case Rep 2014; 20: bcr2013201625. [DOI:10.1136/bcr-2013-201625]
5. Varenna M, Zucchi F, Binelli L, Failoni S, Gallazzi M, Sinigaglia L. Intravenous pamidronate in the treatment of transient osteoporosis of the hip. Bone 2002; 31: 96-101. [DOI:10.1016/S8756-3282(02)00812-8]
6. Schapira D, Braun Moscovici Y, Gutierrez G, Nahir AM. Severe transient osteoporosis of the hip during pregnancy. Successful treatment with intravenous biphosphonates. Clin Exp Rheumatol 2003; 21: 107-110.
7. Grossman JM, Gordon R, Ranganath VK, Deal C, Caplan L, Chen W, et al. American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid‐induced osteoporosis. Arthritis Care Res 2010; 62: 1515-1526. [DOI:10.1002/acr.20295]
8. Thomas E, Cox C, Murphy D, Beddard K. Hip fracture during labour due to transient osteoporosis of the hip in pregnancy. J Obstet Gynaecol 2000; 20: 197-198. [DOI:10.1080/01443610063110]
9. Oliveri B, Parisi MS, Zeni S, Mautalen C. Mineral and bone mass changes during pregnancy and lactation. Nutrition 2004; 20: 235-240. [DOI:10.1016/j.nut.2003.10.011]
10. Roberts D, Brown J, Medley N, Dalziel SR. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 2017; 3: CD004454. [DOI:10.1002/14651858.CD004454.pub3]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


© 2019 All Rights Reserved | International Journal of Reproductive BioMedicine

Designed & Developed by : Yektaweb